Cancer has many sly ways in which it tricks the immune system into sparing it or even into boosting its spread. Now, however, new research is throwing a wrench in cancer’s deception plans. A molecule that scientists have designed stops cancerous cells from tricking the immune system into sustaining their growth.
One such way involves the so-called myeloid cells. These are a key weapon in the immune system’s armory. Myeloid cells are both crucial for the body’s innate immune response and its adaptive response against a wide range of pathogens.
In theory, myeloid cells should attack invaders such as cancerous cells. But the latter trick the former into “thinking” that cancer cells are actually a part of the body that something has damaged. As a result, the tumour cells rope the myeloid cells into helping them divide and grow.
New research, published in the journal Nature Communications, reveals a novel target for immunotherapy, which can stop cancer from recruiting myeloid cells.
Most individuals who have not been affected by childhood cancer mistakenly believe that childhood cancer is caused by genetic or environmental factors, not simply bad luck, according to a new study by medical researchers at UNSW.
The team of researchers has highlighted community beliefs about what causes cancer in children, an area which remains understudied.
“Few childhood cancers are attributed to genetics or environmental factors, so when children are diagnosed with cancer, families often wonder ‘why me/why us‘?” said lead author Janine Vetsch, postdoctoral research candidate from UNSW Sydney in Australia.
The attributed cause of cancer in childhood cancer patients and their primary caregivers differ to those of adult-onset cancers. Most childhood cancer patients are diagnosed at a young age (often between 0 and 5 years). Children are rarely exposed to carcinogens or long-term environmental factors, or engaging in risky health behaviours.
Christmas is not a happy time for everyone – there are many individuals for whom the Festive Season is very painful as it is the time that they miss those who are gone the most.
For parents who have lost a child, whether to cancer or anything else, this is a really, really, difficult time of the year because Christmas is about the children, after all…
Today we would like to take a moment to send out some love to all parents who have lost a child/children.
While the first Christmas is particularly poignant, each Christmas without your child will bring its own challenges, and each parent has to grieve in his or her own way.
There is not much that anyone can say that will take away your pain, but we here at the Little Fighters Cancer Trust would just like to let you know that we are holding you close in our hearts today and are sending you as much Love & Peace as your heart can hold.
✫ Sending you Angel Blessings ✫
( `\( ). .•°*”˜ ☆¸.•´¯`•.☆..✫ (⁀‵⁀,)
..` /♪\_/¯…………`•.¸¸. . . . . . .✫ ⋎´
…\ \ …
…./ /… ✫ Sprinkling Love, Light & Healing ✫
….\/ …. ✫ Peace, Love & Harmony Your Way ✫
The Little Fighters Cancer Trust would like to thank every one of our Donors, Supporters, Ambassadors, Volunteers & Staff for everything that YOU have done to make the lives of our Little Fighters and their Families just that bit easier throughout 2018.
This has been a very difficult year for most people, but thanks to you all, LFCT managed to still take care of the most vulnerable children and their families with advice, information, love and practical assistance.
We did various outreaches to our Little Fighters in hospital as well as at home, and apart from the thousands of presents, clothes, blankest and snack-packs, we also managed to send every one of our registered families a Family Care Package every month so that they at least had all the basics plus some toys for all the kids in the family.
We also had a lovely Christmas Party (sponsored by the Lions, Paarl) for our local Little Fighters and their Families and every Little Fighter plus each of their siblings – Nationally – were sent a lovely Christmas present together with the Family Festive Season Care Package.
Thanks to your donations and thanks to #KargoInternational, there will be Joy and Feasting in all our Registered Little Fighter Families this Festive Season.
Crazy Nomad Jason Doyle and his good friend Tony Visser started their epic Fundraising Ride from Johannesburg to Cape Town (approximately 1 400 kms) on motorised bicycles to raise funds for the Little Fighters Cancer Trust, last Saturday, 15 December.
The guys left from Melrose Arch on Saturday and have been making good time each day despite having to keep off the major highways due to their motorised bicycles only having 60cc engines (which means LOTS of pedaling) and dealing with some really bad gravel roads.
Fortunately they are quite flexible re their planned route and made some adjustments so that the road on Monday was not as bad as Sunday’s road….
Team LFCT is starting to get very excited, but not as excited as Crazy Nomad Jason Doyle and his good friend Tony Visser, who will be starting their epic first of its kind fundraising tour from Johannesburg to Cape Town this coming Friday, 15 December 2018.
They will be doing a Fundraising Ride from Johannesburg to Cape Town (approximately 1 400 kms) on motorised bicycles to raise funds for the Little Fighters Cancer Trust.
The trip will take our riders on the back roads, starting at Melrose Arch, Johannesburg on 15 December 2018 and everyone is invited to witness their send-off which promises to be quite spectacular. Hundreds of Motorcycles from various clubs around Gauteng will escort them out of Johannesburg.
If all goes according to plan, our intrepid riders should arrive in Cape Town on 30 December 2018.
The Paediatric Brain Tumor Foundation’s app is bringing imaginary friends to life in hospitals and cancer treatment centers.
A three-eared rabbit stands on Bridgette Czarnecki’s hospital bed. He playfully wiggles his ear and adjusts his yellow bow tie.
“You’re stronger than you know,” he tells the 8-year-old. “I wish I was that strong.”
A flying pink-haired cow swoops in, pirouetting in the air. “Believe in yourself,” she says in a gentle voice. “I sure do.”
Nearby a friendly green monster smiles and waves. “Never give up, kid. Never give up.”
They’re all part of the Imaginary Friend Society, and they are exactly as billed: a figment of the imagination. For Czarnecki, who was diagnosed with a brain tumor in November 2017, they were a welcome distraction from the stress and anxiety of MRIs and chemotherapy while she was treated at the Children’s Hospital Los Angeles through February.
Czarnecki summoned the characters from a touchscreen above her hospital bed and the Imaginary Friend Society app developed by the Pediatric Brain Tumor Foundation. The app uses augmented reality, which overlays digital images on top of what you’re seeing in the real world.
“It makes me feel happy,” Czarnecki tells me.
The Little Fighters Cancer Trust would like to send out a big shout to Elli Koutsouvelis and Universal Music Africa for the FANTASTIC donation of R25 000 worth of product for our Family Festive Care Packages.
Our offices are full of great goodies that were delivered on Monday and we are happily falling all over them as we get ready to sort and pack all the wonderful goodies we have, including Christmas presents for our Beneficiaries and their siblings across the country.
Our Onco Parents are also well taken care of – in the form of a wonderful Care Package filled to the brim with food, toiletries, cleaning products, personal hygiene items and a few treats for the Festive Season so that they too can enjoy a bit of a break from worrying about the devil cancer and have sufficient to eat over the Festive Period.
“What is my child’s prognosis?” This seemingly simple but critical question is often among the first that parents will ask their child’s oncologist after hearing that their child has been diagnosed with cancer.
Yet, while the question may be simple, answering it can be extremely complicated. In general terms, oncologists can provide statistics relating to 5-year survival rates for many different types of brain tumours in children.
These general statistics, however, cannot predict an outcome for any one child. Each child’s individual prognosis will depend on the unique circumstances of their tumor and its response to treatment.
A smartphone app that includes artificial intelligence elements may be able to reduce the effects of cancer-related pain, according to recent research presented at the 2018 American Society of Clinical Oncology (ASCO) Palliative and Supportive Care in Oncology Symposium.
The app, named ePAL, was designed and studied as part of a collaboration between Partners HealthCare Pivot Labs, the Massachusetts General Hospital Division of Palliative Care, and the Massachusetts General Hospital Cancer Center.
“There is a significant shortage of palliative care providers, which will only worsen in the future as our population ages,” lead study author Mihir M. Kamdar, M.D., associate director of the Division of Palliative Care and an interventional pain physician at Massachusetts General Hospital in Boston, said in a statement. “This is one of the reasons why technology solutions to help manage palliative care challenges, such as cancer pain, are so important.”