Four-Stranded DNA Could Help Develop Targeted Cancer Treatments


four-stranded-dnaTargeted cancer therapies are an important area of precision medicine – where information about an individual patient’s genes and proteins are used to prevent, diagnose, and treat disease – which is why they are currently the focus of much research and development into new anti-cancer treatments.

Researchers from the University of Cambridge in the United Kingdom recently published a paper in the journal Nature Genetics, could wherein they state that their findings also have implications for cancer diagnostics and the development of new targeted treatments.

A main difference between targeted cancer therapy and standard chemotherapy (chemo) is that most chemo treatments act on all rapidly dividing cells – cancerous and healthy alike. The aim of targeted therapy is to single out only the cancer cells, without affecting healthy cells.

In order to single out cancer cells as a basis for treatment, researchers have to find features that are either unique to or more common in cancer cells than healthy cells, such as particular molecular pathways or genetic characteristics.

Read the rest of this entry

Celebrating Heini – Brain Cancer


heini-sept-16-1September is International Childhood Cancer Awareness Month and once again the Little Fighters Cancer Trust is hard at work sharing everything we can regarding Childhood Cancer and trying to raise Childhood Cancer Awareness by sharing information and Personal Stories with you.

Today we are once again sharing the story of Little Heinrich van Straaten (Heini). We have shared his story before, but we feel that we need to share it again as this Little Fighter is still fighting every day of his life as a result of brain cancer.

The Little Fighters Cancer Trust would like to sincerely thank all our Onco Parents that have shared with us in the hope that their stories can help other parents who have children that are ill but are not sure what the problem is, and to raise Childhood Cancer Awareness so that earlier diagnosis can be done.

We will continue to publish more poems and stories by Onco Parents throughout this month as we work hard to bring Childhood Cancer to the fore and spread Childhood Cancer Awareness – all in the effort to inform and educate other parents to the ravages of Childhood Cancer and to remind everyone that

The Best Defence against Childhood Cancer is Awareness and Early Diagnosis

Read the rest of this entry

We Need to DO MORE for Child Cancer Awareness


childhood_cancer_hope_bannerCancer is a horrific word, one that rightly generates fear in the hearts of people regardless of race, gender, age or income bracket.

Hearing the words Childhood Cancer is possibly even worse, because it strikes numbing fear in the heart of a parent whose job it is to protect their offspring and yet they know that they are helpless against the monster called Childhood Cancer.

In many ways, cancer is the great equaliser; it kills indiscriminately; it does not care who you are, what you are or how many people love and need you. It can kill you just the same.

One reason cancer is so terrifying is the fact that the disease can take so many forms. And it’s because of this that so many dedicated activists work to raise Awareness for the fight against a plethora of cancers, and why, apart from everything else that the Little Fighters Cancer Trust does throughout the year, we also make it our priority to spread Childhood Cancer Awareness throughout the year, not only during Childhood Cancer Awareness Month.

The Little Fighters Cancer Trust spreads not only awareness around the various types of Childhood Cancer, but also around Early Warning Signs of Childhood Cancer, because

The Best Defence against Childhood Cancer is Awareness and Early Diagnosis

Read the rest of this entry

Coping with Late Effects of Childhood Cancer Treatment


Late Effects of Childhood Cancer TreatmentAround 80% of Children with Cancer survive at least 5 years these days thanks to advances in treatment, and most of those children will continue on to live a normal life-time.

Unfortunately, the selfsame treatments that are helping Children with Cancer to overcome the cancer, are themselves causing various health problems later on in these children’s lives.

Most side-effects from the cancer itself and from the cancer treatments appear during or just after treatment, and go away within a fairly short time.

Some problems, however, may never go away or may not show up until months or years after treatment.These problems are called late effects.

Due to the fact that more children with cancer now survive into adulthood, their long-term health and these late effects have become more evident and because doctors are more aware of the late side-effects, they will look out for them in careful follow-ups and can therefore find and treat any late effects as early as possible.

Every Child with Cancer that is undergoing cancer treatment is unique; treatments vary from child to child and from one type of cancer to another. Late effects will also vary, and depend mostly on the type of treatment used and the doses given.

Read the rest of this entry

Childhood Cancer Research Landscape Report


childhood-cancer-researchCancer is the leading cause of death by disease in the United States for children ages 1 to 19, with more than 14,500 children ages 1 to 19 in the U.S. facing a diagnosis this year. Although cancer in children is much rarer than in adults, the effects can be worse since it occurs so early in life and the late effects from the disease and treatments can last a lifetime.

Recognizing that progress is still needed in childhood cancer, the American Cancer Society and Alliance for Childhood Cancer created this report to describe the process by which childhood cancer drugs are developed—from basic research through to clinical trials and drug approval.

By articulating how new therapies are developed and understanding how this process is both similar and different than the process for adult drugs, this report aims to identify challenges throughout the process so that efforts can be directed to overcome barriers to progress in childhood cancer research.

Read the rest of this entry

Sorry & Thank You, My Hero


childhood_cancer_awareness_September is International Childhood Cancer Awareness Month and once again the Little Fighters Cancer Trust is hard at work sharing everything we can regarding Childhood Cancer and trying to raise Childhood Cancer Awareness by sharing information and Personal Stories with you.

Today we are  sharing another poem filled with heartache, anguish, pain, guilt, thankfulness and all those other emotions that a parent of a Child with Cancer goes through, written by Reece Barends’ mother, Ashleigh Barends aka da mamma.

The Little Fighters Cancer Trust would like to sincerely thank all our Onco Parents that have shared with us in the hope that their stories can help other parents who have children that are ill but are not sure what the problem is, and to raise Childhood Cancer Awareness so that earlier diagnosis can be done.

We will continue to publish more poems and stories by Onco Parents throughout this month as we work hard to bring Childhood Cancer to the fore and spread Childhood Cancer Awareness – all in the effort to inform and educate other parents to the ravages of Childhood Cancer and to remind everyone that

The Best Defence against Childhood Cancer is Awareness and Early Diagnosis

Read the rest of this entry

Brain Cancer Overtakes Leukemia as Top Cause of Cancer Deaths in Children


brain cancer awareness typographyLeukaemia is no longer the No. 1 cause of cancer deaths in children – brain cancer has taken its place, according to a new report.

Paediatric cancer death rates have been dropping overall since the mid-1970s, according to a report released Sept. 16th from the National Center for Health Statistics. The report details changes in cancer death rates among children and teens ages 1 to 19, from 1999 to 2014.

Lead author Sally Curtin, demographer and statistician at the NCHS, which is part of the Centers for Disease Control and Prevention (CDC), said:

The shift from leukemia to brain cancer as the leading site of cancer death is a noteworthy development in the history of childhood cancer as it was always leukemia until quite recently,”

There were still 1,785 cancer deaths in children and adolescents in 2014, according to Curtin, and Brain cancer and leukaemia accounted for more than 50% of those.

In 1999, 6/20 cancer deaths among children were due to leukaemia, and about 5/20 were due to brain cancer, according to the numbers in the report. By 2014, those numbers had reversed.

Read the rest of this entry

My Perfect 10


love_you_foreverSeptember is International Childhood Cancer Awareness Month and once again the Little Fighters Cancer Trust is hard at work sharing everything we can regarding Childhood Cancer and trying to raise Childhood Cancer Awareness by sharing information and Personal Stories with you.

Today we are  sharing another poem filled with heartache, anguish, loss, and all those other emotions that a parent who has lost a Child to Cancer goes through, written by Michelle Nel, mother of Ryan Nel whose story we brought to you earlier this month.

The Little Fighters Cancer Trust would like to sincerely thank all our Onco Parents that have shared with us in the hope that their stories can help other parents who have children that are ill but are not sure what the problem is, and to raise Childhood Cancer Awareness so that earlier diagnosis can be done.

We will continue to publish more poems and stories by Onco Parents throughout this month as we work hard to bring Childhood Cancer to the fore and spread Childhood Cancer Awareness – all in the effort to inform and educate other parents to the ravages of Childhood Cancer and to remind everyone that

The Best Defence against Childhood Cancer is Awareness and Early Diagnosis

 

Read the rest of this entry

The Reality of Childhood Cancer


awareness ribbonSeptember is International Childhood Cancer Awareness Month and once again the Little Fighters Cancer Trust is hard at work sharing everything we can regarding Childhood Cancer and trying to raise Childhood Cancer Awareness by sharing information and Personal Stories with you.

Today we are  sharing a video with you that may not be fun to watch, but we are doing so in order for people to SEE what Childhood Cancer looks like, what The Reality of Childhood Cancer really is for so many Children and their Families.

THIS is why we are spreading Childhood Cancer Awareness – so that fewer children and there families have to go through THIS…

The Best Defence against Childhood Cancer is Awareness and Early Diagnosis

Read the rest of this entry

The Greatest Gift is Hope


hope_matters_childhood_cancerSeptember is International Childhood Cancer Awareness Month and once again the Little Fighters Cancer Trust is hard at work sharing everything we can regarding Childhood Cancer and trying to raise Childhood Cancer Awareness by sharing information and Personal Stories with you.

Today we are  sharing a poem of encouragement to others going through tough times, written by Reece Barends’ mother, Ashleigh Barends aka da mamma.

The Little Fighters Cancer Trust would like to sincerely thank all our Onco Parents that have shared with us in the hope that their stories can help other parents who have children that are ill but are not sure what the problem is, and to raise Childhood Cancer Awareness so that earlier diagnosis can be done.

We will continue to publish more poems and stories by Onco Parents throughout this month as we work hard to bring Childhood Cancer to the fore and spread Childhood Cancer Awareness – all in the effort to inform and educate other parents to the ravages of Childhood Cancer and to remind everyone that

The Best Defence against Childhood Cancer is Awareness and Early Diagnosis

Read the rest of this entry

Raising Awareness Around Second Opinions


awareness_childhood_cancer_boxing_penguinSeptember is International Childhood Cancer Awareness Month therefore we at the  Little Fighters Cancer Trust have been and still are doing triple time to spread as much information as we can about Childhood Cancer Awareness and the  Early Warning Signs of Childhood Cancer.

Too many children in developing countries, including South Africa, are still dying from Childhood Cancer – most of them due to the fact that knowledge about Childhood Cancer is scarce therefore many children are either not correctly diagnosed or are diagnosed too late for effective treatment.

The more aware people are of Childhood Cancer and its Early Warning Signs, the more early diagnoses there will be, ergo the higher South Africa’s Childhood Cancer survival rates will be.

Today we are also raising awareness of another kind as regards Childhood Cancer, though, via a guest-post, and that is awareness around the importance of getting a second opinion.

We have edited this guest-post slightly in order for it to be more relevant to South African/African individuals….

The Best Defence against Childhood Cancer is Awareness and Early Diagnosis

Read the rest of this entry

Celebrating Ethan Jacobs – Rhabdomyosarcoma


ethanSeptember is International Childhood Cancer Awareness Month and once again the Little Fighters Cancer Trust is hard at work sharing everything we can regarding Childhood Cancer and trying to raise Childhood Cancer Awareness by sharing information and Personal Stories with you.

Today we are  sharing the abbreviated version of Ethan Jacob’s story with you, as written by his mother, Gila.

We are specifically sharing it today as it is Ethan’s 5th BIRTHDAY TODAY and we thought it a fitting tribute to his courage to publish this on the anniversary of his birth!

Happy 5th Birthday, Ethan, from all of us here at the Little Fighters Cancer Trust – with TONS of love and good wishes. You are an AWESOME Warrior, Little Man and we salute your strength and courage!

Most Onco Parents (as parents of Children with Cancer are called) get some form of relief from all the pain and pressures of Childhood cancer from writing down how they feel. It is one way of getting all those emotions out that one just cannot always share with others.

The Little Fighters Cancer Trust would like to sincerely thank Gila for once again sharing Ethan’s story with us in the hope that it can help other parents who have children that are ill but are not sure what the problem is, and to raise Childhood Cancer Awareness so that earlier diagnosis can be done, as it was in Ethan’s case.

We will be publishing more poems and stories by Onco Parents throughout this month as we work hard to bring Childhood Cancer to the fore and spread Childhood Cancer Awareness – all in the effort to inform and educate other parents to the ravages of Childhood Cancer and to remind everyone that

The Best Defence against Childhood Cancer is Awareness and Early Diagnosis

Read the rest of this entry

%d bloggers like this: