Researchers Engineer A ‘Cancer Differentiation Therapy’ For Leukaemia.


Some great strides being made in Leukaemia Research…

Stanford scientists change human leukemia cells into harmless immune cells - healthinnovations

Researchers at the Stanford University have discovered that when a certain aggressive leukemia is causing havoc in the body, the solution may be to force the cancer cells to grow up and behave.  After a chance observation in the lab, the researchers found a method that can cause dangerous leukemia cells to mature into harmless immune cells known as macrophages.  The study is published in the Proceedings of the National Academy of Sciences.

B-cell acute lymphoblastic leukemia with a mutation called the Philadelphia chromosome is a particularly aggressive cancer with poor outcomes state the team, so finding potential treatments is particularly exciting.

The researchers made the key observation after collecting leukemia cells from a patient and trying to keep the cells alive in a culture plate.  They were throwing everything at them to help them survive when they noted that some of the cancer cells in culture were changing shape and size into what looked like macrophages.  The team looked at previous studies, which showed that early B-cell mouse progenitor cells could be forced to become macrophages when exposed to certain transcription factors, proteins that bind to certain DNA sequences.

Read the Full Article on Health Innovations

 

 

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About LFCT

This is a blog about CHILDHOOD CANCER and CHILDHOOD CANCER AWARENESS Little Fighters Cancer Trust is a non-profit organisation that offers support and aid to Children with Cancer and their families. When a child is diagnosed with cancer it affects the whole family. One of the parents, usually the mother, must give up their job to care for the child and this creates financial problems for the family. In South Africa especially the majority of these families are not well-to-do; many of them are rural. A diagnosis of cancer can wipe out any family’s finances, let alone a poor family. The costs of special medications, special diets, hospital stays, transport to and from the hospital or clinic and accommodation and food costs for the mother who spends most of the time at her child’s bedside are astronomical. These are the people and problems that fall through the cracks, and these are the people that Little Fighters Cancer Trust has pledged to help in any way possible. LFCT takes a holistic approach to assisting the Children with Cancer and their Families, with the main aim to be the preservation of individual dignity and pride. Little Fighters Cancer Trust also focuses on promotion and advocacy of National Childhood Cancer Awareness in an effort to increase awareness of Early Warning Signs of Childhood Cancer. This would result in earlier diagnosis, giving the Child with Cancer more of a chance at Treatment and Survival. See "About" for more Background info

Posted on 19 March, 2015, in Blog, Research and tagged , , , , , . Bookmark the permalink. Leave a comment.

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