Fibrolamellar Liver Cancer Research

Fibrolamellar Hepatocellular Carcinoma is a liver cancer that strikes mostly teens and young adults.  Fibrolamellar represents less than 1% of teen and young adult cancers, but that doesn’t mean it is insignificant.   

Because it is so rare, very little is known about Fibrolamellar. Until now. Research teams are now working on it with the help of scientists, surgeons and, as this video shows, some bright and determined patients. This is a story about rare cancer research, patient empowerment, and what we can all do to get involved and help find a cure.

Hepatocellular_carcinomaFibrolamellar- (fibro-la-mel-lar) is our abbreviated name for – Fibrolamellar Hepatocellular Carcinoma which is a rare form of liver cancer that usually occurs in young adults who have no history of liver disease. Each year, approximately 200 people are diagnosed with this cancer worldwide. Patients typically present with a palpable abdominal mass but no symptoms, although pain, weight loss and jaundice may occur. The typical treatment is surgical removal of the tumor. When the tumor cannot be removed surgically or when there is distant spread, chemotherapy is used. There is no standard chemotherapy regimen so the chemo cocktail varies from patient to patient.

Fibrolamellar Facts

  • Fibrolamellar strikes males and females alike
  • Risk factors for fibrolamellar remain unidentified
  • Currently, there are no effective treatment options other than liver resection surgery
  • It effects primarily teens and young adults (although cases as young as 2 and as old as 74 are known)
  • The fibrolamellar variant of hepatocellular carcinoma differs from the “classical” form of hepatocellular carcinoma in several important aspects including:

FHCMost patients with fibrolamellar do not have underlying cirrhosis of the liver

Hepatitis B infection is very uncommon in patients with fibrolamellar

Serum levels of alpha-fetoprotein are usually not elevated in patients with fibrolamellar

  • Only two organs in the body have an ability to regenerate themselves: the liver and the skin
  • Initial diagnosis generally comes from symptoms arising with advanced disease
  • There could be a link between fibrolamellar and gynecomastia, in that the hormonal influence of the fibrolamellar cancer cells cause the gynecomastia. (Gynecomastia is a condition of pubescent boys/men where they show excessive breast tissue.)
  • Fibrolamellar was first identified in the 1950’s

Please visit the Fibrolamellar Cancer Foundation website for more information on Fibrolamellar Hepatocellular Carcinoma


About LFCT

This is a blog about CHILDHOOD CANCER and CHILDHOOD CANCER AWARENESS Little Fighters Cancer Trust is a non-profit organisation that offers support and aid to Children with Cancer and their families. When a child is diagnosed with cancer it affects the whole family. One of the parents, usually the mother, must give up their job to care for the child and this creates financial problems for the family. In South Africa especially the majority of these families are not well-to-do; many of them are rural. A diagnosis of cancer can wipe out any family’s finances, let alone a poor family. The costs of special medications, special diets, hospital stays, transport to and from the hospital or clinic and accommodation and food costs for the mother who spends most of the time at her child’s bedside are astronomical. These are the people and problems that fall through the cracks, and these are the people that Little Fighters Cancer Trust has pledged to help in any way possible. LFCT takes a holistic approach to assisting the Children with Cancer and their Families, with the main aim to be the preservation of individual dignity and pride. Little Fighters Cancer Trust also focuses on promotion and advocacy of National Childhood Cancer Awareness in an effort to increase awareness of Early Warning Signs of Childhood Cancer. This would result in earlier diagnosis, giving the Child with Cancer more of a chance at Treatment and Survival. See "About" for more Background info

Posted on 25 September, 2015, in Blog, Research, Videos and tagged , , , , , , . Bookmark the permalink. 2 Comments.

  1. Your style is unique in comparison to other people I’ve read stuff from.
    Many thanks for posting when you have the opportunity, Guess I will just book mark this page.


Please help us to Raise Childhood Cancer Awareness by Commenting and Sharing

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.

My Name is Chuma

a blog from a Cape Town inner city artist

The Average South African

Food // Travel // Lifestyle

You Are The Cure

Campaign for children with Leukaemia

Knitting Rays of Hope

Spreading Hope...a hat at a time.


Inspired by ordinary people doing extraordinary things

Surviving The Bubble

Jamie Hutchings, Public speaker, leukemia survivor and depression fighter

Sharing my learnings of being a mother

Art of Social Work

Kristina Sargent

fonzandcancer blogging to encourage.

Sharing my journey with you.

%d bloggers like this: