What Happened to the EBC-46 Miracle Cancer Drug?


Back in 2014, researchers published the results of a study in the journal PLoS One that showed the complete destruction of tumours, without relapse, in 75% of laboratory mice treated with direct injections of EBC-46 into the cancerous cells. In some cases, this destruction occurred in as little as 48 hours.

Dr. Glen Boyle was the lead author of that study, conducted by a team of cancer scientists at the Queensland Institute of Medical Research, Australia as well as the private pharmaceutical company QBiotics.  The team extracted a compound from seeds contained in the berry of the Blushwood tree (Fontainea picrosperma), which only grows in the Atherton Tablelands, an area of Rainforest in the North of Queensland.

At the time, Boyle stated that “in most cases a single injection starts killing the cancer off in 4-5 hours.” He also said “the compound works in three ways – it kills the tumour, cuts off the blood supply and activates the immune system to clear it all up.”

In extremely broad brushstrokes, researchers posit that the compound achieves these goals primarily by activating an enzyme called Protein Kinase C, though the exact mechanisms remain unclear.

In December 2016 an article entitled “Scientists find Australian berry to cure cancer in 48 hours!” started doing the rounds and is still being widely shared, but is this 100% true??

Before posting something on this blog, I thoroughly research the subject on various trusted cancer and research sites, as well as searching across the web for the most current information available, and regarding this subject, this is what I have found:

QBiotics holds the patent to EBC-46 and trials were first conducted on mice, cats, dogs, and horses through direct injections, first with melanoma models as well as cancers of the head and neck, where the response and cure were long-term and ‘enduring’ with little or no relapse in more than 70% of the pre-clinical cases.

Work then moved on to cancers of the colon, breast and prostate cancers, and the results showed a 75% success rate.

QBiotics moved on to Human trials; 8 different patients with 4 different cancers were treated across Australia. The cancers – melanoma, squamous cell carcinoma, basal cell carcinoma and breast adenocarcinoma, were all successfully treated.

According to  Dr. Victoria Gordon, CEO of QBiotics, none of the patients showed any side-effects:

It’s proving our theory that it’s not species-specific, and it’s not tumour-specific either, because it’s actually working in a range of tumours.

According to QBiotics, animal studies have been successful enough to bring EBC-46 to the trial phase as a medicine for tumors in dogs and horses, with future trials in the works for cats:

In treatment of over 100 dogs, cats and horses, intralesional injection of EBC-46 has successfully ablated or significantly palliated a range of advanced, inoperable tumours (melanomas, sarcomas, carcinomas, mast cell tumours and sarcoids) while causing no significant long-term side effects. A topical formulation of EBC-46 has also been used to successfully treat ulcerative squamous cell carcinomas on cats and horses.

QBiotics has begun a Phase I trial of EBC-46 in humans, as stated on their website:

EBC-46 is currently being evaluated for safety in a Clinical Phase I trial in patients with cutaneous or subcutaneous solid tumours. Such tumours include melanoma, head and neck cancer, SCC and BCC of the skin and Merckel cell carcinoma. In this trial, EBC-46 is delivered locally in a single treatment by direct injection into tumours. The trial is being conducted in Australia by clinicians in Sydney, Melbourne, Brisbane and Adelaide.

Australia’s National Health and Medical Research Council describes a Phase I clinical trial as follows:

Phase I clinical trials are done to test a new biomedical intervention for the first time in a small group of people (e.g. 20-80) to evaluate safety (e.g. to determine a safe dosage range and identify side effects).

 

More can be read on the human trials in this study, “Phase 1 dose-escalation study of EBC-46 given by intratumoral injection to patients with refractory cutaneous and subcutaneous tumors.”

or HERE

So, in conclusion, while EBC-46 has shown a lot of promise, we still have a long way to go before it is approved or disapproved for human use, so don’t go out picking blushwood berries just yet… and be wary of sites that are advertising the “Blushwood Berry Extract Miracle Cure”

 

 

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About LFCT

This is a blog about CHILDHOOD CANCER and CHILDHOOD CANCER AWARENESS Little Fighters Cancer Trust is a non-profit organisation that offers support and aid to Children with Cancer and their families. When a child is diagnosed with cancer it affects the whole family. One of the parents, usually the mother, must give up their job to care for the child and this creates financial problems for the family. In South Africa especially the majority of these families are not well-to-do; many of them are rural. A diagnosis of cancer can wipe out any family’s finances, let alone a poor family. The costs of special medications, special diets, hospital stays, transport to and from the hospital or clinic and accommodation and food costs for the mother who spends most of the time at her child’s bedside are astronomical. These are the people and problems that fall through the cracks, and these are the people that Little Fighters Cancer Trust has pledged to help in any way possible. LFCT takes a holistic approach to assisting the Children with Cancer and their Families, with the main aim to be the preservation of individual dignity and pride. Little Fighters Cancer Trust also focuses on promotion and advocacy of National Childhood Cancer Awareness in an effort to increase awareness of Early Warning Signs of Childhood Cancer. This would result in earlier diagnosis, giving the Child with Cancer more of a chance at Treatment and Survival. See "About" for more Background info

Posted on 21 March, 2017, in Blog, Research and tagged , , , , , , , . Bookmark the permalink. 6 Comments.

  1. I am trying to type LOSING, sorry.

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    • Haha, don’t worry, Helen, I got it 😀

      As far as why they don’t push it through, who knows? It takes years and loads of $$ for all this research and to get it to human-trial stage… Hopefully we will have more treatments soon, especially for Childhood Cancer which has been sorely neglected 😦

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  2. I meant looking money from other cancer drugs.

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  3. This seems very promising yet they have been researching since 2014, why not push it through to save some lives?
    If cancer can be cured so quickly the big money makers will be looking on other drugs and there may not be a big profit margin on this new treatment. No wonder people are cynical and not trusting traditional medicine anymore.

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  4. Hi,
    Thanks for this information. I had been searching various sites to find more about this EBC 46 injection.
    I am trying to get more info on how to get in touch with the researchers behind this treatment. And if one wants to put their hand up for becoming the candidate for the trial.

    Like

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