Many individuals have been espousing the use of high doses of Vitamin C for cancer patients for years, but were shouted down by the majority, especially Big Pharma, because Vitamin C is not a massive money-spinner.
Now, however, new clinical trials have found that it is safe to regularly infuse brain and lung cancer patients with 800 – 1,000 times the daily recommended amount of vitamin C as a potential strategy to improve outcomes of standard cancer treatments.
In a work presented March 30, 2017 in Cancer Cell, University of Iowa researchers have also shown pathways by which altered iron metabolism in cancer cells, and not normal cells, lead to increased sensitivity to cancer cell killing caused by high dose vitamin C.
“This paper reveals a metabolic frailty in cancer cells that is based on their own production of oxidizing agents that allows us to utilize existing redox active compounds, like vitamin C, to sensitize cancer cells to radiation and chemotherapy,” says co-author Garry Buettner, who was one of the first to propose that cancer cells might have a vulnerability to redox active compounds over 40 years ago. Buettner, along with study senior authors Bryan Allen and Douglas Spitz, are faculty members at the University of Iowa’s Department of Radiation Oncology, Free Radical and Radiation Biology Program, in the Holden Comprehensive Cancer Center. Read the rest of this entry