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Chimeric Antigen Receptor (CAR) T-Cell Therapy is a form of cancer immunotherapy which seeks to sharpen and strengthen the immune system’s inherent cancer-fighting powers.
CAR T-Cell Therapy was approved in August 2017 ~ the first time that the Food and Drug Administration (FDA) approved CAR T-cell therapy for a form of cancer ~ for the treatment of paediatric and young adult patients with B-cell ALL that has relapsed or hasn’t responded to previous treatments.
Acute Lymphoblastic Leukaemia (ALL) is a type of leukaemia in which a group of white blood cells, called lymphocytes, are affected. Leukaemia is the most common form of cancer in children, and about 80% of children with leukaemia have Acute Lymphoblastic Leukaemia.
CAR T-Cell Therapy involves treating patients with modified versions of their own immune system T cells – white blood cells that help protect the body from disease.
Lewis Silverman, MD, Clinical Director of the Hematologic Malignancy Center at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, said:
“It’s a very exciting development in our ability to treat childhood ALL. It offers hope to those that we haven’t been able to treat with conventional therapy. This is a hugely exciting time in childhood leukaemia research”
Today we put out a very urgent plea for help to make a wish come true for young Aleem, a 5-year-old boy with terminal cancer.
Little Fighter Aleem Bowman was born on 25 July 2012. When he was admitted to Red Cross Children’s Hospital on 15 September 2016, he was diagnosed with Stage IV Neuroblastoma.
Aleem went through RCCH High Risk Neuroblastoma Protocol until April 2017, which included tests, scans, blood work, regular transfusions, hospitalisation, intensive chemotherapy and other treatments, and loads more.
Mommy Kaneez, a single mother, has had to handle a lot, and unfortunately this became even worse when the doctors informed her recently that there are simply no more treatment options for Aleem. He was on maintenance chemo for a short while, which was given purely to extend the time he has with his family, but even the maintenance chemo has now been stopped, as it serves no purpose anymore, and could now be harmful.
Aleem lives with his mommy (who had to give up her job to look after Aleem) and his older sister Kami at Kaneez’s elderly Parents’ home. Things have been very difficult for this family and The Little Fighters Cancer Trust has been offering whatever assistance we could such as food, clothing, bedding, and other practical needs since 7 October 2016.
Aleem was friends with another Little Fighter who lost his Fight last year, but who, before he died got his greatest wish and was able to visit Durban and have a very special interaction with the dolphins at Ushaka Marine World. Aleem saw the photographs, and has been talking about the dolphins for months!
Last week LFCT received a letter from Aleem’s Oncologist, positive about this travel and clearing him medically for the trip!
Dandelion is a very rich source of beta-carotene which we convert into vitamin A. This flowering plant is also rich in vitamin C, fibre, potassium, iron, calcium, magnesium, zinc, and phosphorus.
It’s a good way to get B complex vitamins, trace minerals, organic sodium, and even some vitamin D too. Dandelion also contains protein – more than spinach. It has been eaten for thousands of years as a food and as a medicine to treat anaemia, scurvy, skin problems, blood disorders, and depression.
Dandelion root is tougher and hardier than the leaf and is often used in decoctions and tinctures for this reason. The powder is often added in coffee substitutes. The root is considered a natural diuretic and is sometimes used for this purpose.
Dandelion root and leaf are often listed as the ingredients of teas and poultices for abscesses and sores, especially on the breast and in female health remedies as they can help support lactation and remedy urinary issues.
There’s something magical about making a wish while blowing dandelion petals through the air. Just one glance at a dandelion brings back childhood memories. And while some consider them pesky weeds, dandelion offers a treasure trove of healing benefits.
Dandelion greens are used in so many health applications today. Whether steamed, sautéed, used in soup, or boiled with water and brown sugar for tea, the greens of these weeds are considered an herbal medicine.
The extract (from dandelion root) is purported to work by inducing apoptosis in the cancer cells. To put this another way, this process forces the cancer cells to commit suicide without damaging the healthy cells in any way.
Dandelion Root is frequently used by herbalists to treat liver, kidney, and gallbladder problems. Dandelion Root has been used in China for certain kinds of cancers for centuries. Dandelion is a source of a variety of nutrients and the leaves and root contain Vitamins (A,C, K and B-vitamins) as well as minerals (including magnesium, zinc, potassium, iron, calcium and choline).
In an effort to improve outcomes for patients with some of the deadliest Childhood Cancers, St. Jude Children’s Research Hospital scientists have created the world’s largest collection of Childhood solid tumour samples, drug-sensitivity data and related information and have made the resource available at no charge to the global scientific community.
St. Jude and the Howard Hughes Medical Institute collaborated to create the resource, known as the Childhood Solid Tumour Network (CSTN), which was launched in 2013.
“Survival rates for children with recurrent solid tumours have not improved significantly in more than 20 years and remain below 30 %,” said corresponding author Michael Dyer, Ph.D., Chair of the St. Jude Department of Developmental Neurobiology and a Howard Hughes Medical Institute investigator. “This research will change that by promoting scientific collaboration to leverage the efforts of researchers worldwide to advance understanding and ultimately treatment of Childhood solid tumours.”
There are hundreds of ways to heal cancer and enzyme therapy is seen to be a very effective treatment.
The idea of healing cancer with enzymes was first discovered by Dr John Beard, an embryologist who spent 20 years researching cancer.
He found that pancreatic enzymes were not present in the blood of cancer patients. Although his first article was published in 1902, his theory about cancer still holds up to rigorous scientific scrutiny.
Dr John Beard proposed in 1906 that pancreatic proteolytic digestive enzymes represent the body’s main defence against cancer, and that enzyme therapy would be useful as a treatment for all types of cancer.
During the first two decades of the twentieth century, Dr Beard’s thesis attracted some attention in academic circles, and several case reports in the medical literature documented tumour regression and even remission in terminal cancer patients treated with proteolytic enzymes.
In 1911, Dr Beard published a monograph entitled The Enzyme Therapy of Cancer and Its Scientific Basis, which summarised his therapy and the supporting evidence.
After Dr Beard’s death in 1923, the enzyme therapy was largely forgotten. Periodically, other practitioners have rediscovered Dr Beard’s work, and used pancreatic proteolytic enzymes as an alternative cancer treatment.
The mapping of the human genome has ushered in the age of precision cancer medicine, in which an individual’s treatment can be tailored to the specific genetic abnormalities of his or her disease.
In recent years, much attention has been brought to genetic testing for cancer risk, particularly around Angelina Jolie and her decision to undergo preventative surgeries.
Amy Kindstedt, a 9-year-old, was diagnosed with Pleuropulmonary Blastoma (PPB), a rare tumour of the lung, in 2014. PPB tumours can progress from a more benign to a more aggressive type if not detected early. Because she had a particularly aggressive form, her treatment required the removal of her left lung, radiation, and a year of chemotherapy
Knowing that PPB is often caused by mutations in a gene known as DICER1, her Dana-Farber/Boston Children’s care team tested Amy for the gene. Once they found she had a mutation in the gene, her parents, grandparents, and younger brothers Hunter and Thatcher were tested as well.
It has long been known that animals, especially dogs, are great companions and also wonderful therapy tools for those who are ill.
Dogs can also sense/smell cancer in a human long before they even know there is anything wrong…
This is a bit of a different story of a dog and a little boy though – Ollie the pug is a therapy dog at Boston Children’s Hospital, and in March, 2016 he paid a bedside visit to 7-year-old Carter Mock.
The thing is, both Ollie and the young lad had lost a limb to osteosarcoma, a cancer of the bone. Ollie’s left front leg was amputated at the shoulder and a tumour was removed from Carter’s left leg bone, after which surgeons fashioned a new knee from his ankle in a procedure called rotationplasty.
The similarities don’t end there…
While most people know Garth Taylor for his chart-topping radio hits, few know he is an avid fitness fanatic and that kickboxing is his second passion.
Garth won the SA Amateur Kickboxing Championships in the lightweight category in 2014.
In an effort to raise funds for the Little Fighters Cancer Trust (LFCT) during Childhood Cancer Awareness month, Garth returns to the ring at the White Collar Boxing 19 event at Scarlet Ribbon, in Modderfontein TONIGHT, September 15.
“I lost my sister to cancer. Having watched what she went through as an adult fighting this disease, I can only imagine how much worse it is for children to be fighting this battle,” comments Garth. “I figured, how bad could it be? Me stepping into the ring and getting punched around for kids who are fighting for their lives every single day.
“I hope that the general public and companies will pledge towards this campaign and that we can raise funds and help make a difference. Cancer is a bully, and I will be fighting with everything I have for this cause,” he adds.
Herbs and plants were the original treatments for many illnesses and injuries people faced. As such, cannabis or marijuana use dates back centuries. It popped up in Western medicine in the 19th century as a means of relieving pain, inflammation, and spasms.
Today, marijuana use can spark some serious debate, even when considered for medical use only. But regardless of how you feel about its use, more cancer patients are turning to marijuana for a number of reasons.
Marijuana is not legal for use everywhere and researchers have their own concerns about potential side effects. For some patients, however, the benefits can be invaluable as they go through treatment.