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Childhood Cancer: Part V (v): Bone Marrow & Peripheral Blood Stem Cell Transplants


In Part 1 of this series we explained that this series of articles is not meant to be medical advice, but a guide that may help you as a parent of a newly diagnosed child with cancer cope just a bit better. Information is knowledge, and never more so than when you are dealing with childhood cancer!

These articles are meant to help you be the key part of your child’s treatment that you will need to be. Take what works for you according to your situation and your child’s temperament, personality, fears, strengths, and how they deal with adversity, and leave what does not pertain to your situation.

Part 5 deals with Different Types of Treatment and Possible Side-Effects of that treatment. As this is quite a long section, it has been split it into 5(i) Surgery 5(ii) Chemotherapy 5(iii) Radiation Therapy 5(iv) Immunotherapy and 5(v) Bone Marrow & Peripheral Blood Stem Cell Transplants.

Complementary and Alternative Medicine treatment (CAM) is very involved and will contain a lot of information, so that will be dealt with separately in Part 6 of this series of articles.

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Graft-Versus-Host Disease


Some individuals being treated for certain cancers may undergo a Stem Cell Transplant along with Chemotherapy or Radiation Therapy. In Stem Cell Transplantation, healthy stem cells are taken either from themselves or a donor.

An allogeneic transplant is a procedure which involves using blood-forming stem cells (cells from which all blood cells develop) from a genetically similar, but not identical, cancer-free donor who matches the recipient’s tissue type. Most commonly, donors are a close relative, such as a sibling, but could also be an unrelated donor.

Using a donor for stem cell transplants offers what is called a graft-versus-cancer effect, in which the donor’s stem cells (graft) may attack any cancer cells found in the recipient (host).

Unfortunately, however, a stem cell transplant can also cause a condition called graft-versus-host-disease (GVHD).

GVHD is a serious and potentially life-threatening condition in which the donor cells attack the recipient’s healthy cells, causing a range of medical problems.

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Childhood Cancer: A General Guide for Parents Part V (v): Bone Marrow & Peripheral Blood Stem Cell Transplants


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In Part 1 of this series we explained that this series of articles is not meant to be medical advice, but a guide that may help you as a parent of a newly diagnosed child with cancer cope just a bit better. Information is knowledge, and never more so than when you are dealing with childhood cancer!

These articles are meant to help you be the key part of your child’s treatment that you will need to be. Take what works for you according to your situation and your child’s temperament, personality, fears, strengths, and how they deal with adversity, and leave what does not pertain to your situation.

Part 5 will deal with Different Types of Treatment and Possible Side-Effects of that treatment. As this is quite a long section, I will split it into 5(i) Surgery 5(ii) Chemotherapy 5(iii) Radiation Therapy 5(iv) Immunotherapy and 5(v) Bone Marrow & Peripheral Blood Stem Cell Transplants.

Complementary and Alternative Medicine treatment (CAM) is very involved and will contain a lot of information, so that will be dealt with separately in Part 6 of this series of articles.

Read the rest of this entry

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