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Childhood Cancer: Part V (v): Bone Marrow & Peripheral Blood Stem Cell Transplants


In Part 1 of this series we explained that this series of articles is not meant to be medical advice, but a guide that may help you as a parent of a newly diagnosed child with cancer cope just a bit better. Information is knowledge, and never more so than when you are dealing with childhood cancer!

These articles are meant to help you be the key part of your child’s treatment that you will need to be. Take what works for you according to your situation and your child’s temperament, personality, fears, strengths, and how they deal with adversity, and leave what does not pertain to your situation.

Part 5 deals with Different Types of Treatment and Possible Side-Effects of that treatment. As this is quite a long section, it has been split it into 5(i) Surgery 5(ii) Chemotherapy 5(iii) Radiation Therapy 5(iv) Immunotherapy and 5(v) Bone Marrow & Peripheral Blood Stem Cell Transplants.

Complementary and Alternative Medicine treatment (CAM) is very involved and will contain a lot of information, so that will be dealt with separately in Part 6 of this series of articles.

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How do Blood Cancers Differ in Adults & Adolescents?


Survival rates associated with blood cancers such as Leukaemia, Lymphoma, and Multiple Myeloma have gone up for patients of all ages in recent years. This increase has however been relatively smaller in adolescents and young adults than in children and older adults.

According to researchers, there are likely to be multiple reasons for this. Part of the answer lies in the basic biology of tumours – differences in the genetic makeup of cancers in young adults that make such cancers less responsive to standard therapies.

In Acute Lymphocytic Leukaemia (ALL)… also known as Acute Lymphoblastic Leukaemia, researchers have recently identified a genetic sub-type, known as Philadelphia chromosome-like (Ph-like) ALL, that becomes more prevalent with age and possibly peaks in young adulthood.

Philadelphia chromosome-like (Ph-like) ALL has a poorer prognosis in adolescents and young adults, according to Daniel DeAngelo, MD, PhD, director of Clinical and Translational Research for the Adult Leukaemia Program at Dana-Farber. Ph-like ALL has a pattern of gene activity similar to a sub-type called Philadelphia chromosome-positive (Ph+) ALL.

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Hear What Happened When This Adorable 65-Year Old Woman With Cancer Took Mushrooms


magic-mushrooms-varieties-3The 65 year old psychotherapist Estalyn Walcoff was devastated when she was told that she’s suffering from untreatable lymphoma 5 years ago. But, realizing that having negative thoughts won’t do her any good, she decided to incorporate a spiritual outlook into her life.

She began looking for ways to help herself and came across a study that required test patients for consumption of psilocybin, the active ingredient in ‘magic mushrooms’, with hopes in treating anxiety and depression in cancer patients.

When she got in NYU where the testing took place, she was amazed by the environment. “There was a couch, flowers, and books, and it seemed not-study-like” she recalls. “Jeff and Seema had a wonderful ritual with the three of us, intending for how that day would go, which I thought was lovely. I also asked if I could read a poem, and play a song that really moved me, to set an intention for the day too.”

Even though “magic mushrooms” weren’t new to her since she’d tried them few times in her early 20’s, this time it was different. This time, she took a journey through the dark barrels of her own mind.

She soon realized that this anxiety was actually a level of her own mind.

“I began feeling that I was actually holding the pain of the world in some way. I had been listening to black spiritual, and I felt the pain in the woman’s voice who was singing the song. I felt the whole gestalt of slavery, and what it is like to pull people out of their homes and take them here to this country and treat them like animals, and I sobbed and sobbed because of that.“ Read the rest of this entry

Researchers Identify Mechanism to Control Enzyme Crucial For Boosting Immunity


featured image Study sheds new light on a crucial enzyme for the immune response - healthinnovations

A new study from researchers at the IRCM sheds light on a mechanism affecting AID, a crucial enzyme for the immune response. The scientific breakthrough could eventually improve the way researchers treat the common flu, as well as lymphoma and leukemia.

The researchers study white blood cells, called B-lymphocytes, whose main function is to produce antibodies to fight against infections. More specifically, they focus on an enzyme found in B cells known as AID, or activation-induced deaminase.  The team explain that AID is crucial for an efficient antibody response.  However, high levels of AID can also have harmful effects and lead to certain cancer-causing mutations. The objective is to find the perfect level of AID activity to maximise the protection it provides to the body while reducing the risk of damage it can cause to cells.

Read the Full Article on Health Innovations

 

 

Childhood Cancer: A General Guide for Parents Part V (v): Bone Marrow & Peripheral Blood Stem Cell Transplants


hope_cancer_pics10

In Part 1 of this series we explained that this series of articles is not meant to be medical advice, but a guide that may help you as a parent of a newly diagnosed child with cancer cope just a bit better. Information is knowledge, and never more so than when you are dealing with childhood cancer!

These articles are meant to help you be the key part of your child’s treatment that you will need to be. Take what works for you according to your situation and your child’s temperament, personality, fears, strengths, and how they deal with adversity, and leave what does not pertain to your situation.

Part 5 will deal with Different Types of Treatment and Possible Side-Effects of that treatment. As this is quite a long section, I will split it into 5(i) Surgery 5(ii) Chemotherapy 5(iii) Radiation Therapy 5(iv) Immunotherapy and 5(v) Bone Marrow & Peripheral Blood Stem Cell Transplants.

Complementary and Alternative Medicine treatment (CAM) is very involved and will contain a lot of information, so that will be dealt with separately in Part 6 of this series of articles.

Read the rest of this entry

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