Up until now, drug companies have been free to decide whether to pursue treatments for paediatric cancers as part of their work on adult cancers or not, and this has led to a minimal amount of new drugs specifically for paediatric cancers being developed.
An estimated 2,000 children die of cancer annually, and the overall incidence of childhood cancer has been slowly increasing since 1975 – there has been a 13% rise in Childhood Cancer in the past 20 years alone.
Despite significant advances against certain pediatric cancers, including Acute Lymphoblastic Leukemia, there are still some types of cancer for which there are few or no effective treatments.
The truth is that new drug development in pediatric cancer is extremely slow, often lagging way behind adult treatments, and few compounds are designed specifically for children.
The sad truth is that Childhood cancers make up less than 1% of all cancers diagnosed each year, and that is is not much of a market for drug makers, who rack up an estimated $1.4 billion in out-of-pocket costs while bringing a novel drug to market.
They won’t have much choice going forward!!
Collated Childhood cancer statistics in sub Saharan Africa have been published for the first time as a monograph in the peer reviewed journal ecancermedicalscience, allowing researchers and policymakers a critical new insight into the impact of paediatric cancer across this region.
On the African continent, only South Africa operates a childhood cancer registry on the national level.
This new study brings together data from 16 of the smaller localised registers, which, as members of the African Cancer Registry Network (AFCRN), have been evaluated as achieving adequate coverage of their target population. The study has allowed for the collection of this scattered knowledge for the first time and presents it in an accessible format.
The cancers are classified according to the third revision of the International Classification of Childhood Cancer (ICCC-3) and recorded rates in Africa are compared with those in childhood populations in the UK, France, and the USA.
When Children with Cancer have to undergo Radiation Treatment, they often get scared or nervous because they do not have an understanding of the process and the machines involved.
To remedy this, young children are usually given a general anaesthetic, even though the long-term side effects are still unknown.
Instead of relying on anaesthesia, Danielle Crump, BSN, RN, worked to develop the Paediatric Training Program within the Radiation Department of Johns Hopkins Hospital.
This initiative saves time and money while avoiding any risks or complications that might come from administering anaesthesia to a paediatric patient.
It is winter in South Africa, and that means that we need to eat more, eat more hot food, and eat more nutritional food in order to stave off the bitter cold weather, influenza, the sniffles etc.
This is vitally important for our Little Fighters, as Children with Cancer need all of their strength to build up their immune system which is compromised due to the cancer and as a result of the treatments such as Chemotherapy and Radiation Therapy.
Children with Cancer have to follow a nutritionally specific diet, which is often impossible for cancer-affected families to follow due to lack of funds.
In excess of 50% of the individual Childhood Cancer-affected families that are supported by the Little Fighters Cancer Trust have lost one income due to the child’s diagnosis. LFCT supports in excess of 100 Childhood Cancer-affected Families with groceries every month!
With one parent in the hospital for months, sometimes years on end, the sole breadwinner struggles to make ends meet at home. The Little Fighters Cancer Trust ensures that these families have food in the home while the Child with Cancer is in and out of hospital via our Feeding Our Families project.
We need YOUR help to put food on the table for many of our Little Fighters and their Families who are really struggling. Read the rest of this entry
While we understand that when one’s child has cancer and does not seem to be getting better one is desperate enough to try ANYTHING, one should be aware of some of the cancer myths that are out there such as “Cancer is a Fungus – and Sodium Bicarbonate is the Cure.”
This rather strange and frankly ridiculous “theory” seems to originate in the fact that “cancer is always white.”
Let’s just put this myth to rest once and for all – cancer cells are clearly not fungal in origin, and cancer isn’t always white.
Sodium Bicarbonate reduces stomach acid. It is used as an antacid to treat heartburn, indigestion, and upset stomach. Sodium bicarbonate is a very quick-acting antacid; it should, however, be used only for temporary relief. Sodium Bicarbonate DOES NOT cure cancer!
Wheat-grass contains chlorophyll, which has almost the same molecular structure as haemoglobin. Chlorophyll increases haemoglobin production, which means that more oxygen gets to the cancer.
Wheat-grass also contains Selenium and Laetrile, both of which have anti-cancer properties. Both Chlorophyll and selenium also help build the immune system.
Wheat-grass contains at least 13 vitamins, of which several are antioxidants, including Vitamin B12, and various minerals and trace elements, including selenium, as well as all 20 amino acids.
Back in the 40s and 50s, cancer patients were being treated by having their blood extracted, bombarded with ultraviolet light and then put back into the body.
The blood (actually the haemoglobin) “remembered” the ultraviolet frequencies (i.e. the haemoglobin continued to vibrate after being exposed to the frequencies) after the blood was put back into the body.
Wheat-grass can be used instead of extracted blood because the haemoglobin molecules and the chlorophyll molecules have some very key similarities.
It is important to eat small meals more often while undergoing conventional cancer treatments such as Surgery, Chemotherapy and Radiation Therapy.
For those who are suffering side-effects such as dysphasia, sore mouths or nausea, consuming a nutrient dense smoothie for one meal and then trying some sun-dried fruits (without sugar) and untoasted nuts as a snack a few hours later is a good idea.
A lunch with salad greens, bitter herbs, apple slices, berries and a dressing made with lemon and olive oil, a pinch of cayenne pepper and avocado makes an exceptionally nutrient-dense meal.
This type of Ayurvedic diet plan will increase your sense of taste, smell, and appetite and help one heal and feel good.
One of the side-effects of undergoing chemotherapy and radiation treatments for cancer is that the appetite is often affected; most food tastes like cardboard so not very appealing. The constant nausea also generally makes one not feel like putting anything in your mouth.
Despite the many side-effects and complications caused by conventional cancer treatments, it is vital that a person with cancer consumes sufficient nutrients to help the body recover.
The human body is essentially designed to heal itself, but when it is overwhelmed by poisons, pain, and the inability to smell or taste, food might be the last thing a person with cancer wants. It is important therefore that you ensure that you choose foods for your child with cancer that will stimulate their appetite while delivering the biochemical components necessary to rebuild damaged tissues and fight against infection and inflammation. These foods should also contain properties that eliminate nausea, stimulate appetite, and heal the gastrointestinal tract.
Conventional Cancer Treatments such as Chemotherapy and Radiation Therapy unfortunately generally come with a variety of not-so-nice side effects, such as diarrhoea, one of the more dangerous side effects.
Diarrhoea can not only be painful, but it also removes important nutrients, probiotics, and water from the body. As a result, diarrhoea puts one at a higher risk for more trauma from infection and dehydration.
It is important to manage these side effects immediately to prevent further complications that will weaken your body. The best way to heal is to ensure that you eat only healthy foods and avoid problematic foods that are going to worsen your diarrhoea.
A university degree is linked to a heightened risk of developing a brain tumor, suggests a large observational study, published online in the Journal of Epidemiology & Community Health.
Gliomas, in particular, were more common among people who had studied at university for at least three years than they were among those who didn’t go on to higher education, the data show.
The researchers base their findings on more than 4.3 million Swedes, all of whom were born between 1911 and 1961 and living in Sweden in 1991.
They were monitored between 1993 and 2010 to see if they developed a primary brain tumor, and information on educational attainment, disposable income, marital status, and occupation was obtained from national insurance, labour market,and national census data.
During the monitoring period, 1.1 million people died and more than 48,000 emigrated, but 5735 of the men and 7101 of the women developed a brain tumour. Read the rest of this entry
For many, a brain cancer diagnosis remains a death sentence. The life expectancy of those suffering from gliomas, the most common and most aggressive form of brain tumour, has changed little in 40 years.
On average, patients die within 9-12 months of receiving the diagnosis. Yet the most cruel aspect of this illness is the way it attacks individuals from within – steadily robbing them of their ability to perform basic tasks and making it increasingly difficult for them to interact with loved ones and the world around them.
Brain cancer alters personalities. It impairs mental functions, disrupts speech, paralyses limbs and, ultimately, leaves its victims with little freedom or dignity. It not only takes lives, it drastically reduces quality of life.
The Beer for Brains Foundation is an Arizona-based non-profit organisation of craft-beer lovers, distributors and brewers, who are committed to raising public awareness about brain cancer, Engendering Compassion for its victims and Helping Fund ground-breaking research leading to a cure. Read the rest of this entry
Many individuals have been espousing the use of high doses of Vitamin C for cancer patients for years, but were shouted down by the majority, especially Big Pharma, because Vitamin C is not a massive money-spinner.
Now, however, new clinical trials have found that it is safe to regularly infuse brain and lung cancer patients with 800 – 1,000 times the daily recommended amount of vitamin C as a potential strategy to improve outcomes of standard cancer treatments.
In a work presented March 30, 2017 in Cancer Cell, University of Iowa researchers have also shown pathways by which altered iron metabolism in cancer cells, and not normal cells, lead to increased sensitivity to cancer cell killing caused by high dose vitamin C.
“This paper reveals a metabolic frailty in cancer cells that is based on their own production of oxidizing agents that allows us to utilize existing redox active compounds, like vitamin C, to sensitize cancer cells to radiation and chemotherapy,” says co-author Garry Buettner, who was one of the first to propose that cancer cells might have a vulnerability to redox active compounds over 40 years ago. Buettner, along with study senior authors Bryan Allen and Douglas Spitz, are faculty members at the University of Iowa’s Department of Radiation Oncology, Free Radical and Radiation Biology Program, in the Holden Comprehensive Cancer Center. Read the rest of this entry
Finding out that your child has cancer is devastating enough in itself, but what is even worse are the months and years that follow… the fight against this monstrous disease, the toll it takes on your child with cancer, your other children, your spouse, your marriage/relationship, your familial relationships, your friendships, your work, your own health, and your finances.
When we talk about The Business of Cancer, we are not only talking about the financial costs of Childhood Cancer Treatment, although they are high, but everything that it takes to deal with a diagnosis of Childhood Cancer…
A typical cancer patient’s treatment can easily cost hundreds of thousands of rands per year:
“Depending on the kind of cancer and the complexity of a case, treatment per year can cost less than R10 000, or way over R1 million,” according to Dr Ernst Marais, Operations Executive at the Independent Clinical Oncology Network (ICON). Read the rest of this entry
Oncology Nursing Month, celebrated the entire month of May, is a chance to recognize the outstanding contributions of oncology nurses.
The official theme selected for 2017 is: FEARLESS COMMITMENT; ENDLESS COMPASSION.
Oncology Nurses explain the diagnosis, guide patients through treatment, celebrate their victories, and comfort them through the unimaginable. No matter what, they provide fearless commitment and endless compassion to their patients every day. That’s why we celebrate the oncology nurse this month.
Oncology nurses, and especially Paediatric Oncology Nurses, provide steadfast and selfless care for their patients. Individuals who are diagnosed with cancer, as well as the parents of Children with Cancer, naturally go through a wide range of emotions; they may feel confused, angry, afraid or just numb, and they may wonder how others find the strength to remain positive through all the obstacles that come with the diagnosis. Read the rest of this entry
A research study, Radiotherapy after high-dose chemotherapy with autologous hematopoietic cell rescue: Quality assessment of Head Start III, published in Paediatric Blood & Cancer, shows that reduced Radiation Therapy results in worse outcomes.
“This study shows that attention to the timing, dose, and location of radiation therapy is crucial,” Kenneth K. Wong, MD, a radiation oncologist at Children’s Hospital Los Angeles and first author on the study.
The paper is a qualitative assessment of the Head Start III trial which avoids or delays Radiation Therapy in children with brain tumours. The studies represent an innovative approach to the treatment of malignant brain tumours – using high dose Chemotherapy followed by transfusion of blood stem cells – as a substitute for radiation in younger children, where the late side effects of radiation to the developing brain can be particularly detrimental. If disease persists after this course of treatment or if the child is older, they receive radiation therapy.
In the latest Head Start III study, only 31 of 220 children received radiation – of those, a subset (8 of 25), consisting of children 6 years of age or younger, had deviations from the treatment plan.
“Parents or providers may want to delay the start of radiation or reduce the dose or area of exposure – particularly in very young children,” said Wong. “But in a study already limiting radiation exposure – patients with these kinds of protocol violations experienced worse outcomes.”
Patients that received radiation therapy treatment according to protocol and within 11 weeks of recovery from stem cell transfusion showed improved overall survival.